Department of Neurobiology, University of Osnabrück


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The Department of Neurobiology is part of the 3rd funding period of the Collaborative Research Center 944 (SFB 944) "Physiology and Dynamics of Cellular Microcompartments" of the University of Osnabrück. (Homepage of the SFB) (Press release - in German)

Claudia Schob, Fabio Morellini, Ora Ohana, Lidia Bakota, Mariya V. Hrynchak, Roland Brandt, Marco D. Brockmann, Nicole Cichon, Henrike Hartung, Ileana Hanganu-Opatz, Vanessa Kraus, Sarah Scharf, Irm Herrmans-Borgmeyer, Michaela Schweizer, Dietmar Kuhl, Markus Wöhr, Karl J. Vörckel, Julia Calzada-Wack, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabě de Angelis, Craig C. Garner, Hans-Jürgen Kreienkamp and Stefan Kindler. Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice. Translational Psychiatry, in press.

9th Westerberger Herbsttagung on the Perspectives of Molecular Neurobiology: "Psychological and biological aspects of explicit and implicit memory", Thursday, September 27, 2018, University of Osnabrück
(Poster) (Program) (Press release - in German)

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The Department of Neurobiology is part of the new University-funded Research Training Group “EvoCell – Cellular mechanisms of evolutionary innovation”. (General Information)

Anne Gauthier-Kemper*, María Suárez Alonso*, Frederik Sündermann, Benedikt Niewidok, Maria-Pilar Fernandez, Lidia Bakota, Jürgen J. Heinisch, Roland Brandt (2018) Annexins A2 and A6 interact with the extreme N-terminus of tau and thereby contribute to tau’s axonal localization (*both authors contributed equally). J. Biol. Chem. 293:8065-8076

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Schematic representation showing how tau’s interaction to annexin A6 may contribute to axonal retention of tau at physiological conditions.

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Benedikt Niewidok*, Maxim Igaev*, Abel Pereira da Graca, Andre Strassner, Christine Lenzen, Christian P. Richter, Jacob Piehler, Rainer Kurre and Roland Brandt (2018) Single-Molecule Imaging Reveals Dynamic Biphasic Partition of RNA-Binding Proteins in Stress Granules (*both authors contributed equally). J. Cell Biol. 217:1303–1318.

The PhD/Postdoc Career Center of the University of Osnabrück (ZePrOs): Concepts and Service (S. Mehlmann, Zentrum für Promovierende und Postdocs (ZePrOs)) (Presentation for download)

The Department of Neurobiology (PI R. Brandt) cooperates with the Department of Pharmacy, Central University of Rajasthan (India, PI R. Malik) on the development of GSK3b inhibitors for the treatment of Alzheimer’s disease. The project is supported by the German Academic exchange service (DAAD).  


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Microtubules in the neurodegenerative triad of Alzheimer’s disease
(from: Brandt and Bakota (2017) Microtubule dynamics and the neurodegenerative triad of Alzheimer’s disease: The hidden connection. J. Neurochem. 143:409-417)

April 26-27, 2018: EUROTAU 2018, Lille, France (R. Brandt: Talk).
July 4-6, 2018: 11th International Meeting on Substrate-Integrated Microelectrode Arrays (MEAs), Reutlingen (N. Abreu: Poster).
July 7-11, 2018: 11th FENS Forum of Neuroscience, Berlin (C. Gach: Poster).
July 6-29, 2018: International Summer School: Biomembranes & Cellular Microcompartments, Osnabrück (B. Niewidok: Poster)
July 27, 2018: Universita degli Studi di Milano, Dipartimento di Bioscienze, Milano, Italy (R. Brandt: Talk)
August 28 - September 1, 2018: Cold Spring Harbor Meeting "Single Biomolecules", USA (R. Brandt: Talk)
Sept. 20-21, 2018: Retreat of the Collaborative Research Center 944 (SFB 944), Osnabrück (M. Carrera: Talk and Poster; B. Niewidok: Poster and Flash presentation)
Sept. 20-22, 2018: Meeting of the GBM-Study Goup Molecular Neurobiology: "Dynamics of the Nervous System in Health and Disease", Marburg (C. Gach: Talk).
Sept. 27, 2018: 9th Westerberger Herbsttagung on the Perspectives of Molecular Neurobiology, Osnabrück (N. Abreu: Poster; M. Hrynchak: Poster, M. Carrera: Talk and Poster)
Oct. 11, 2018: Hochschule Kaiserslautern (L. Bakota: Talk).
Oct. 19-21, 2018: 2nd Sino-German Symposium: "Development and Maintenance of Brain Function: From Basic Mechanisms to Disease", Berlin (R. Brandt: Talk).

February 22-23, 2018 (in German): Fortbildungsveranstaltung für Lehrerinnen und Lehrer des Fürstenberg-Gymnasiums Recke zur kindlichen Entwicklungspsychologie: "'I am my connectome' - Wie sich neuronale Netzwerke entwickeln, reifen und verfeinern und was das mit Lernen zu tun hat" (R. Brandt).
March 5, 2018 (in German): Fortbildungsveranstaltung am Institut für Didaktik der Universität Duisburg-Essen "Erinnern, Vergessen und die Alzheimer Erkrankung" (R. Brandt).

Basic Information

In 2002, a new Department of Neurobiology was installed on a lab space of about 200 square meters and a functional space of additional 100 square meters in the Institute of Biology at the University of Osnabrück. The Department belongs to the School of Biology/Chemistry and is associated with the Institute of Cognitive Science. The research of the Department focusses on the mechanisms of neural development and degeneration on the molecular, cellular and systemic level. Techniques include S1 and S2 cell and organotypic culture (including gene transfer with Sindbis and Lentivirus), laser scanning microscopy and quantitative image analysis, electrophysiology (extracellular recordings using microelectrode arrays), and breeding, genotyping and characterization of transgenic mouse lines. Teaching involves participation in the Bachelor and Master programs "Biosciences" and the Bachelor program "Cognitive Sciences". The Department consists of three research groups (AG Bakota, AG Brandt and AG Jeserich (retired)). Every two years, members of the Department organize the Westerberger Herbsttagung. The Department is part of the Collaborative Research Center 944 (SFB 944) and the Center of Cellular Nanoanalytics Osnabrück (CellNanOs).  

Departmental Seminars 2018

Seminar room Neurobiology (room 36-334)

Date Speaker and Title
Tuesday, January 23, 2 pmSpecial Seminar on "Perspectives in Structural and Functional Neurobiology": Understanding Neurodegeneration through Microscopic Imaging and Multi Electrode Array (MEA) Recordings of Mouse and Tissue Culture Models of Alzheimer's Disease (L. Bakota)
Tuesday, January 30, 11 amYearly Safety Instructions: General lab safety, Biological safety (W. Hamann, R. Brandt)
Tuesday, February 13, 11 amThe PhD/Postdoc Career Center of the University of Osnabrück (ZePrOs): Concepts and Service (S. Mehlmann, Zentrum für Promovierende und Postdocs (ZePrOs))
Tuesday, April 24, 11 amNeurobiological Seminar within the SFB: Neuronal Tropomyosins - Function and Regulation (T. Fath, University of New South Wales, Sydney, Australia)
ATTENTION DIFFERENT ROOM: Lecture Hall CellNanOS (38/201)
Tuesday, May 29, 11 amScientific publishing: Authorship and author credit (R. Brandt)
Tuesday, October 30, 11 amMeeting reports part I (N. Abreu, C. Gach)
Tuesday, November 6, 11 amMeeting reports part II (R. Brandt)
Tuesday, November 27, 11 amUpdate on electronic lab books (C. Gach)

Attendance is mandatory for bachelor, master, doctoral and postdoctoral members of the Department and open to everybody.
Seminar language is English