Department of Neurobiology, University of Osnabrück


NOW AVAILABLE: Abstracts of the "8th Westerberger Herbsttagung":
Perspectives of Molecular Neurobiology - From Single Molecules to Systems.
We are happy to announce the winners of the poster prizes:
1. Prize: Jennifer Heck, Leibniz-Institute Magdeburg
2. Prize: Benedikt Niewidok, University of Osnabrück
3. Prize: Tamer Abdelaal, Max-Planck-Institute Göttingen
Image "Home:Poster_wht8.jpg"

JUST ACCEPTED: Lorène Penazzi, Julia Lorengel, Frederik Sündermann, Nataliya Golovyashkina, Stefan Marre, Chantal MB Mathis, Lars Lewejohann, Roland Brandt and Lidia Bakota (2017) DMSO modulates CNS function in a preclinical Alzheimer's disease model. Neuropharmacology 113:434-444.

JUST PUBLISHED: Benedikt Niewidok*, Maxim Igaev*, Frederik Sündermann, Dennis Janning, Lidia Bakota and Roland Brandt. Presence of a carboxyterminal pseudo-repeat and disease-like pseudohyperphosphorylation critically influence tau’s interaction with microtubules in axon-like processes. (*joint first authors) Mol. Biol. Cell 27:3537-3549.

JUST PUBLISHED: Special Issue on "Cytoskeletal Proteins in Health and Neurodegenerative Diseases" in: "Brain Research Bulletin". Guest Editors: Jürgen Götz (University of Queensland, Brisbane, Australia) and Roland Brandt (University of Osnabrück, Germany) (Medline) (Download) (cover) (table of contents).

JUST PUBLISHED: Jürgen Heinisch and Roland Brandt (2016) Signaling pathways and posttranslational modifications of tau in Alzheimer's disease: how humanized can yeast cells become? Microb. Cell 3:132-188.

JUST PUBLISHED: Lorène Penazzi*, Christian Tackenberg*, Adnan Ghori, Nataliya Golovyashkina, Benedikt Niewidok, Karolin Selle, Carlo Ballatore, Amos B. Smith III, Lidia Bakota and Roland Brandt (2016) Abeta-mediated spine changes in the hippocampus are microtubule-dependent and can be reversed by a subnanomolar concentration of the microtubule-stabilizing agent epothilone D. (*joint first authors) Neuropharmacology 105:84-95.

RECENT INTERVIEW: "Der Kampf gegen das Vergessen" NDR - Das Wissenschaftsmagazin (4.3.16; in German)

Basic Information

In 2002, a new Department of Neurobiology was installed on a lab space of about 200 square meters and a functional space of additional 100 square meters in the Faculty of Biology and Chemistry at the University of Osnabrück. The research of the Department focusses on the analysis of mechanisms of neural development and degeneration on the molecular, cellular and systemic level. Techniques include S1 and S2 cell and organotypic culture (including gene transfer with Sindbis and Lentivirus), laser scanning microscopy and quantitative image analysis, electrophysiology (extracellular recordings using microelectrode arrays), and breeding, genotyping and characterization of transgenic mouse lines. Teaching involves participation in the Bachelor and Master programmes "Biology of the Cell" and the Bachelor programme "Cognitive Sciences". The Department consists of three research groups (AG Bakota, AG Brandt and AG Jeserich). Every two years, members of the Department organize the Westerberger Herbsttagung. The Department is part of the Collaborative Research Center 944 (SFB 944), the CellNanOs Initiative (Center of Cellular Nanoanalytics Osnabrück), and is a user of the North-German Supercomputing Alliance (HLRN).  

Departmental Seminars 2016

Seminar room Neurobiology (room 36-334)

Date Speaker and Title
Thursday, January 7, 10-12 amInternational Seminar on Molecular Mechanisms of Neurodegeneration part I (M.R. Carrera (Barcelona, Spain), M. Hrynchak (Viseu, Portugal))
Friday, January 8, 10-12 amInternational Seminar on Molecular Mechanisms of Neurodegeneration part II (K. Stratigi (Heraklion, Greece))
Tuesday, January 26, 11 amYearly Safety Instructions: General lab safety, Biological safety (W. Hamann, R. Brandt)
Tuesday, March 15, 11 amCurrent Concepts in the Electrophysiology of Tauopathy Models (G. Jeserich, A. Ussif)
Tuesday, May 10, 11 amIntroduction to Statistics for Neurobiologists (F. Sündermann, M. Igaev)
Tuesday, May 31, 11 amGood Laboratory Practice - Selected Aspects (R. Brandt)
Monday, June 27, 2 pmSeminar on Live Cell Imaging part I (A.M. Hackel (Oldenburg))
Tuesday, June 28, 1 pmSeminar on Live Cell Imaging part II (C. Gach (Hamburg), C. Omieczynski (Berlin), L. Feldhahn (Leipzig))
Tuesday, November 1, 11 amOpen Access - Principles and Support from the University (S. Boccalini, open access representative of the University of Osnabrück)
Wednesday, November 2, 11 amTau therapeutics in stress-driven brain pathology: exploring the path from depression to Alzheimer's disease (I. Sotiropoulos, University of Minho, Portugal)

Attendance is mandatory for bachelor, master, doctoral and postdoctoral members of the Department and open to everybody.
Seminar language is English