Department of Neurobiology, University of Osnabrück


Christian Conze, Nataliya I. Trushina, Nanci Monteiro-Abreu, Daniel Villar Romero, Eike Wienbeuker, Anna-Sophie Schwarze, Michael Holtmannspötter, Lidia Bakota, Roland Brandt: Redox signaling by hydrogen peroxide modulates axonal microtubule organization and induces a specific phosphorylation signature of microtubule proteins distinct from distress. (bioRxiv)
(Audio summary on ScienceCast)
Image "Home:2024-Redox-Scheme.jpg"

BOOK REVIEW FOR "BIOspektrum 4/24":
Francis Waldvogel, Die Vielfalt der Emergenz: Vom Atom bis zur Natur des Menschen, utb (in German language)

Recent bilateral meeting on Perspectives in Neurobiology:
Image "Home:2024-Announcement-Thomas Fath.JPG"

COMING IN SEPTEMBER: 11th Westerberger Herbsttagung on the Perspectives of Molecular Neurobiology:
On Friday, September 27, 2024, the 11th edition of the traditional Westerberg autumn conference, organized by the Department of Neurobiology, will take place in CellNanOs at the University of Osnabrück.
Mark the date.
Image "Home:2024-11th_WHT_Poster.JPG"
Poster for download

Poster exhibition of the School of Biology/Chemistry in the Botanical Garden from May 1 to October 6, 2024.
Image "Home:2024-Announcement-50years.jpg"

Poster contribution of the Department of Neurobiology: "Von der Zellkultur zur Entwicklung neuer Therapien gegen die Alzheimer Krankheit" (in German language)
Image "Home:2024-Poster-Botanical_Garden.jpg"

BOOK REVIEW FOR "BIOspektrum 2/24":
Matthias Haudel, Theologie und Naturwissenschaft, utb (in German language)

Luca Pinzi*, Christian Conze*, Nicolo Bisi, Gabriele Dalla Torre, Ahmed Soliman, Nanci Monteiro-Abreu, Nataliya I. Trushina, Andrea Krusenbaum, Maryam Khodaei Dolouei, Andrea Hellwig, Michael S. Christodoulou, Daniele Passarella, Lidia Bakota, Giulio Rastelli#, and Roland Brandt#: Quantitative live cell imaging of a tauopathy model enables the identification of a polypharmacological drug candidate that restores physiological microtubule interaction. (Nature Communications) (*joint first authors) (#joint corresponding authors). bioRxiv link.
Image "Home:2024-NatComm.JPG"
(Nikon Microscope Solutions Europe’s Post)

"50 YEARS OF TAU" issue is now published in print (January 2024):

Image "Home:2024-Title-Cytoskeleton.jpg"
(whole issue)
(our contribution: Lidia Bakota and Roland Brandt: Why kiss-and-hop explains that tau does not stabilize microtubules and does not interfere with axonal transport (at physiological conditions))

NEW: „Top 2% Scientists worldwide":
Stanford University has recently released a list that represents the top 2 percent of the most-cited scientists in various disciplines. The database provides standardized information on citations, h-index, co-authorship-adjusted hm-index, citations to papers in different authorship positions, and a composite indicator. Several members of the Faculty of Biology/Chemistry, including Prof. Brandt, are listed as “Top 2% Scientists Worldwide”.

The Department is part of the program “Tailored drug discovery targeting the tubulin code” of the “Centro de Investigaciones Biológicas Margarita Salas” (CSIC; Spain) for the support of international collaborations.

Marina Rierola, Nataliya I. Trushina, Nanci Monteiro-Abreu, Christian Conze, Michael Holtmannspötter, Rainer Kurre, Max Holzer, Thomas Arendt, Jürgen J. Heinisch, Roland Brandt and Lidia Bakota: Tau and α-synuclein shape microtubule organization and microtubule-dependent transport in neuronal dendrites. (bioRxiv)

The Department of Neurobiology participates in the "Forschungsbörse" of the Ministry of Science and Education (Bundesministerium für Bildung und Forschung, BMBF).
University-school partnership "Neurobiologie macht Schule": School visits at the Gymnasium Martinum, Emsdetten (17.01.2024), at the Irena-Sendler-Gesamtschule in Ahaus (28.02.2024), and at the Georgianum in Vreden (15.03.2024).

Basic Information

In 2002, a new Department of Neurobiology was installed on a lab space of about 200 square meters and a functional space of additional 100 square meters in the Institute of Biology at the University of Osnabrück. The Department belongs to the School of Biology/Chemistry and is associated with the Institute of Cognitive Science. The research of the Department focusses on the mechanisms of neural development and degeneration on the molecular, cellular and systemic level (Research Mission). Techniques include S1 and S2 cell and organotypic culture (including gene transfer with Sindbis and Lentivirus), laser scanning microscopy and quantitative image analysis, electrophysiology (extracellular recordings using microelectrode arrays), and breeding, genotyping and characterization of transgenic mouse lines. Teaching involves participation in the Bachelor program "Biologie", the Bachelor program "Cognitive Sciences", the Master program "Biologie/Biology - from Molecules to Organisms" and the Master program "Nanosciences - Materials, Molecules and Cells". The Department consists of three research groups (AG Bakota, AG Brandt and AG Jeserich (retired)). Every two years, members of the Department organize the Westerberger Herbsttagung. The Department is part of the Center of Cellular Nanoanalytics Osnabrück (CellNanOs).  

Departmental Seminars 2024

Seminar room Neurobiology (room 36-334)

Date Speaker and Title
Tuesday, January 30, 11 amYearly Safety Instructions: General lab safety, Biological safety (W. Hamann, R. Brandt)
Tuesday, April 2, 11 amPretalk for PhD defense (N. Abreu)
Tuesday, June 25, 11 amSelected aspects of "good scientific practice": Peer review and preprints - where is the path going? (R. Brandt)
Thursday, July 4, 10-12 amUOS-Macquarie University discussion round on Perspectives of Molecular Neurobiology (with T. Fath, Macquarie University, Sydney, Australia)
Coming soonFELASA Meeting report part 1: "Creating and maintaining genetically altered animals" (L. Bakota)
Coming soonFELASA Meeting report part 2: "Experimental design" (L. Bakota)

Attendance is mandatory for bachelor, master, doctoral and postdoctoral members of the Department and open to everybody.
Seminar language is English